Diesel Exhaust Particles Enhance MUC4 Expression in NCI-H292 Cells and Nasal Epithelial Cells via the p38/CREB Pathway | Zendy

IlHo Park | Zendy; JuHyung Kang | Zendy; Jin Ah Kim | Zendy; JaeMin Shin | Zendy; Heung-Man Lee | Zendy

Open Access

Diesel Exhaust Particles Enhance <b><i>MUC4</i></b> Expression in NCI-H292 Cells and Nasal Epithelial Cells via the p38/CREB Pathway

Author(s) -

IlHo Park,

JuHyung Kang,

Jin Ah Kim,

JaeMin Shin,

Heung-Man Lee

Publication year - 2016

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000453033

Subject(s) - creb , mucin , microbiology and biotechnology , blot , messenger rna , p38 mitogen activated protein kinases , chemistry , biology , mapk/erk pathway , signal transduction , transcription factor , biochemistry , gene

Diesel exhaust particles (DEPs), the major contributors to air pollution, induce inflammatory responses in the nasal epithelium. Overproduction of airway mucins is an important pathogenic finding in inflammatory airway diseases.

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