Optimizing Cerebral Autoregulation May Decrease Neonatal Regional Hypoxic-Ischemic Brain Injury | Zendy

Jennifer K. Lee | Zendy; Andrea Poretti | Zendy; Jamie Perin | Zendy; Thierry A.G.M. Huisman | Zendy; Charlamaine Parkinson | Zendy; Raul ChavezValdez | Zendy; Matthew O’Connor | Zendy; Michael Reyes | Zendy; Jillian Armstrong | Zendy; Jacky M. Jennings | Zendy; Maureen Gilmore | Zendy; Raymond C. Koehler | Zendy; Frances J. Northington | Zendy; Aylin Tekes | Zendy

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Optimizing Cerebral Autoregulation May Decrease Neonatal Regional Hypoxic-Ischemic Brain Injury

Author(s) -

Jennifer K. Lee,

Andrea Poretti,

Jamie Perin,

Thierry A.G.M. Huisman,

Charlamaine Parkinson,

Raul ChavezValdez,

Matthew O’Connor,

Michael Reyes,

Jillian Armstrong,

Jacky M. Jennings,

Maureen Gilmore,

Raymond C. Koehler,

Frances J. Northington,

Aylin Tekes

Publication year - 2016

Publication title -

developmental neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.893

H-Index - 82

eISSN - 1421-9859

pISSN - 0378-5866

DOI - 10.1159/000452833

Subject(s) - medicine , autoregulation , anesthesia , asphyxia , hypoxic ischemic encephalopathy , blood pressure , cerebral autoregulation , hypothermia , traumatic brain injury , hemodynamics , encephalopathy , white matter , cerebral blood flow , mean arterial pressure , intracranial pressure , cardiology , magnetic resonance imaging , heart rate , radiology , psychiatry

Therapeutic hypothermia provides incomplete neuroprotection for neonatal hypoxic-ischemic encephalopathy (HIE). We examined whether hemodynamic goals that support autoregulation are associated with decreased brain injury and whether these relationships are affected by birth asphyxia or vary by anatomic region.

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