Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs among Adults: Clinical Features and Risk Factors for Diagnosis Confirmation
Author(s) -
Eva Gomes,
Luísa Geraldes,
Angéla Gáspár,
Daniela Malheiro,
Susana Cadinha,
Carmo Abreu,
Marta Chambel,
Eugénia Almeida,
Emília Faria
Publication year - 2016
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000452627
Subject(s) - medicine , angioedema , atopy , drug allergy , allergy , provocation test , aspirin , anaphylaxis , drug , population , immunology , nonsteroidal , gastroenterology , pharmacology , pathology , alternative medicine , environmental health
Nonsteroidal anti-inflammatory drugs (NSAIDS) are among the most common causes of drug hypersensitivity (HS) reactions. The diagnosis is based on a careful clinical history, and provocation tests are considered the gold standard for diagnosis. Skin tests have some value to study reactions to pyrazolones. Laboratory investigations are mostly used for research purposes. Different phenotypes have been described.
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