Open AccessSulodexide Protects Contrast-Induced Nephropathy in Sprague-Dawley Rats
Author(s) -
Qing Zhao,
Jianyong Yin,
Zeyuan Lu,
Yiwei Kong,
Guangyuan Zhang,
Binghui Zhao,
Feng Wang
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000452575
Subject(s) - oxidative stress , apoptosis , nephropathy , pharmacology , endocrinology , inflammation , medicine , contrast induced nephropathy , chemistry , biochemistry , diabetes mellitus
Sulodexide is a powerful antithrombin agent with reno-protective property. However, whether it has beneficial effects on Contrast-Induced Nephropathy (CIN) remained elusive. In the current study, we evaluated the therapeutic effects of Sulodexide on CIN and investigated the potential mechanisms.
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