Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF-β1 | Zendy

Yuanyuan Guo | Zendy; Zengxiang Dong | Zendy; Yuanqi Shi | Zendy; Wei Wang | Zendy; Lu Wang | Zendy; Jing Sun | Zendy; Xin Sun | Zendy; Zhen Tian | Zendy; Jianting Yao | Zendy; Zhitao Li | Zendy; Jiali Cheng | Zendy; Ye Tian | Zendy

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Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF-β1

Author(s) -

Yuanyuan Guo,

Zengxiang Dong,

Yuanqi Shi,

Wei Wang,

Lu Wang,

Jing Sun,

Xin Sun,

Zhen Tian,

Jianting Yao,

Zhitao Li,

Jiali Cheng,

Ye Tian

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000452571

Subject(s) - sonodynamic therapy , cardiac fibrosis , transforming growth factor , fibrosis , medicine , signal transduction , protein kinase b , myocardial fibrosis , cancer research , ventricular remodeling , chemistry , microbiology and biotechnology , endocrinology , pathology , heart failure , biology , alternative medicine

Sonodynamic therapy (SDT) is a localized ultrasound-activated therapy for atherosclerosis when combined with a sonosensitizer, 5-aminolevulinic acid (ALA), but whether it can prevent cardiac fibrosis has not been studied. In the present study, we evaluated the effects SDT on fibrogenesis in rat cardiac fibroblasts.

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