Effect of Extracellular Vesicles on Neural Functional Recovery and Immunologic Suppression after Rat Cerebral Apoplexy
Author(s) -
Beilei Hu,
Songfang Chen,
Ming Zou,
Zhiyong He,
Shengmin Shao,
Baohua Liu
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000452533
Subject(s) - immune system , central nervous system , extracellular , nervous system , biology , regeneration (biology) , pathology , medicine , immunology , neuroscience , microbiology and biotechnology
Previous studies have demonstrated that mesenchymal stem cells (MSCs) can promote the recovery of neural function after cerebral apoplexy by secreting multiple cytokines. In addition, cell factor-derived extracellular vesicles play an important role in recovery of neural function. The aim of this study was to determine the effect of extracellular vesicles on neural functional recovery and brain tissue remodeling after cerebral apoplexy in a rat model.
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