Raf Kinase Inhibitory Protein Down-Expression Exacerbates Hepatic Fibrosis In Vivo and In Vitro | Zendy

Quanfang Huang | Zendy; Chunhong Liang | Zendy; Ling Wei | Zendy; Jinlan Nie | Zendy; Shengjuan Lu | Zendy; Chunyuan Lu | Zendy; Lang Zhuo | Zendy; Zhongpeng Lu | Zendy; Xing Lin | Zendy

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Raf Kinase Inhibitory Protein Down-Expression Exacerbates Hepatic Fibrosis In Vivo and In Vitro

Author(s) -

Quanfang Huang,

Chunhong Liang,

Ling Wei,

Jinlan Nie,

Shengjuan Lu,

Chunyuan Lu,

Lang Zhuo,

Zhongpeng Lu,

Xing Lin

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000452524

Subject(s) - hepatic stellate cell , downregulation and upregulation , in vivo , liver injury , fibrosis , cancer research , hepatic fibrosis , mapk/erk pathway , signal transduction , apoptosis , kinase , in vitro , biology , endocrinology , medicine , chemistry , pathology , microbiology and biotechnology , gene , biochemistry

Raf kinase inhibitory protein (RKIP) is closely associated with numerous tumors and participates in their development through regulating the growth, apoptosis, invasion and metastasis of tumor cells. However, the role of RKIP in chronic liver injury and particularly in liver fibrosis is still unclear.

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