The Role Played by Adenosine in Modulating Reflex Sympathetic and Pressor Responses Evoked by Stimulation of TRPV1 in Muscle Afferents | Zendy

Jihong Xing | Zendy; Jianhua Li | Zendy

Open Access

The Role Played by Adenosine in Modulating Reflex Sympathetic and Pressor Responses Evoked by Stimulation of TRPV1 in Muscle Afferents

Author(s) -

Jihong Xing,

Jianhua Li

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000452523

Subject(s) - trpv1 , adenosine , reflex , medicine , stimulation , endocrinology , capsaicin , adenosine a1 receptor , adenosine receptor , agonist , chemistry , dorsal root ganglion , receptor , transient receptor potential channel , anatomy , dorsum

Activation of metabolite-sensitive transient receptor potential vanilloid type 1 (TRPV1) receptors (capsaicin receptors) in afferent nerves of the hindlimb muscles of rats increases renal sympathetic nerve activity (RSNA) and blood pressure (BP) via a reflex mechanism. The purpose of this study was to examine the role of adenosine in modulating the reflex RSNA and BP responses to stimulation of TRPV1.

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