Angiotensin-(1-7) Prevents Skeletal Muscle Atrophy Induced by Transforming Growth Factor Type Beta (TGF-β) via Mas Receptor Activation | Zendy

Johanna Ábrigo | Zendy; Felipe Simón | Zendy; Daniel Cabrera | Zendy; Claudio CabelloVerrugio | Zendy

Open Access

Angiotensin-(1-7) Prevents Skeletal Muscle Atrophy Induced by Transforming Growth Factor Type Beta (TGF-β) via Mas Receptor Activation

Author(s) -

Johanna Ábrigo,

Felipe Simón,

Daniel Cabrera,

Claudio CabelloVerrugio

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000452522

Subject(s) - medicine , endocrinology , myogenesis , skeletal muscle , angiotensin ii , chemistry , muscle atrophy , atrophy , transforming growth factor , receptor , myosin , myostatin , myocyte , biology , biochemistry

Transforming growth factor type beta 1 (TGF-β1) produces skeletal muscle atrophy. Angiotensin-(1-7) (Ang-(1-7)), through the Mas receptor, prevents the skeletal muscle atrophy induced by sepsis, immobilization, or angiotensin II (Ang-II). However, the effect of Ang-(1-7) on muscle wasting induced by TGF-β1 is unknown.

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