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Ischemic Postconditioning-Regulated miR-499 Protects the Rat Heart Against Ischemia/Reperfusion Injury by Inhibiting Apoptosis through PDCD4
Author(s) -
Jianbing Zhu,
Kang Yao,
Qian Wang,
Junjie Guo,
Hongtao Shi,
Leilei Ma,
Haibo Liu,
Wei Gao,
Yunzeng Zou,
Junbo Ge
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000452506
Subject(s) - medicine , myocardial infarction , apoptosis , reperfusion injury , ventricular pressure , lactate dehydrogenase , cardiac function curve , ischemia , left coronary artery , cardiology , tunel assay , terminal deoxynucleotidyl transferase , ventricle , evans blue , creatine kinase , anesthesia , hemodynamics , chemistry , heart failure , immunohistochemistry , biochemistry , enzyme
Here, we determined miR-499 involvement in the protective effect of ischemic postconditioning (IPC) against myocardial ischemia/reperfusion (I/R) injury and identified the underlying mechanisms.

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