Open AccessNonstructural Protein 1 of Tick-Borne Encephalitis Virus Induces Oxidative Stress and Activates Antioxidant Defense by the Nrf2/ARE Pathway
Author(s) -
Yulia Kuzmenko,
Olga A. Smirnova,
Alexander V. Ivanov,
Elizaveta Starodubova,
В. Л. Карпов
Publication year - 2016
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000452160
Subject(s) - microbiology and biotechnology , oxidative stress , transfection , reactive oxygen species , biology , plasmid , chemistry , gene , biochemistry
Infection with tick-borne encephalitis virus (TBEV) causes pathological changes in the central nervous system. However, the possible redox alterations in the infected cells that can contribute to the virus pathogenicity remain unknown.
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