Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency | Zendy

Adda Grimberg | Zendy; Sara A. DiVall | Zendy; Constantin Polychronakos | Zendy; David B. Allen | Zendy; Laurie E. Cohen | Zendy; Jose Bernardo Quintos | Zendy; Wilma C. Rossi | Zendy; Chris Feudtner | Zendy; M. Hassan Murad | Zendy

Open Access

Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency

Author(s) -

Adda Grimberg,

Sara A. DiVall,

Constantin Polychronakos,

David B. Allen,

Laurie E. Cohen,

Jose Bernardo Quintos,

Wilma C. Rossi,

Chris Feudtner,

M. Hassan Murad

Publication year - 2016

Publication title -

hormone research in paediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.816

H-Index - 89

eISSN - 1663-2826

pISSN - 1663-2818

DOI - 10.1159/000452150

Subject(s) - idiopathic short stature , guideline , medicine , growth hormone deficiency , short stature , grading (engineering) , growth hormone , pediatrics , endocrine system , turner syndrome , intensive care medicine , endocrinology , hormone , pathology , civil engineering , engineering

On behalf of the Drug and Therapeutics, and Ethics Committees of the Pediatric Endocrine Society, we sought to update the guidelines published in 2003 on the use of growth hormone (GH). Because idiopathic short stature (ISS) remains a controversial indication, and diagnostic challenges often blur the distinction between ISS, GH deficiency (GHD), and primary IGF-I deficiency (PIGFD), we focused on these three diagnoses, thereby adding recombinant IGF-I therapy to the GH guidelines for the first time.

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