MicroRNAs for the Prediction of Early Response to Sorafenib Treatment in Human Hepatocellular Carcinoma | Zendy

Naoshi Nishida | Zendy; Tadaaki Arizumi | Zendy; Satoru Hagiwara | Zendy; Hiroshi Ida | Zendy; Toshiharu Sakurai | Zendy; Masatoshi Kudo | Zendy

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MicroRNAs for the Prediction of Early Response to Sorafenib Treatment in Human Hepatocellular Carcinoma

Author(s) -

Naoshi Nishida,

Tadaaki Arizumi,

Satoru Hagiwara,

Hiroshi Ida,

Toshiharu Sakurai,

Masatoshi Kudo

Publication year - 2016

Publication title -

liver cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.916

H-Index - 34

eISSN - 2235-1795

pISSN - 1664-5553

DOI - 10.1159/000449475

Subject(s) - sorafenib , hepatocellular carcinoma , medicine , microrna , oncology , gastroenterology , metastasis , cancer , progressive disease , multivariate analysis , disease , response evaluation criteria in solid tumors , biology , biochemistry , gene

Several studies suggest the role of circulating microRNAs (miRNAs) as biomarkers of hepatocellular carcinoma (HCC). However, the serum miRNA profile associated with the response to sorafenib remains to be elucidated. The aim of this study was to clarify the specific miRNAs in serum that could predict the early response of HCC to sorafenib treatment.

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