Open AccessPaget's Disease of the Vulva Treated with Imiquimod: Case Report and Systematic Review of the Literature
Author(s) -
Aşkın Doğan,
Ziad Hilal,
Harald Krentel,
Cem Çetin,
Lukas Hefler,
Christoph Grimm,
Clemens Tempfer
Publication year - 2016
Publication title -
gynecologic and obstetric investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 63
eISSN - 1423-002X
pISSN - 0378-7346
DOI - 10.1159/000449158
Subject(s) - imiquimod , medicine , vulva , dermatology , surgery , resection margin , wide local excision , vulvar neoplasm , resection
Extramammary Paget's disease of the vulva (EPDV) is a rare adenocarcinoma in situ of the vulvar skin and is often resected with involved margins due to its reticular growth pattern. Adjuvant treatment with the immunomodulator imiquimod may be suitable to avoid repeated and mutilating surgery.
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