Clinical Scenario of the Metabolic Syndrome | Zendy

Swantje Brede | Zendy; Georg Serfling | Zendy; Johanna Klement | Zendy; Sebastian Schmid | Zendy; Hendrik Lehnert | Zendy

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Clinical Scenario of the Metabolic Syndrome

Author(s) -

Swantje Brede,

Georg Serfling,

Johanna Klement,

Sebastian Schmid,

Hendrik Lehnert

Publication year - 2016

Publication title -

visceral medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.598

H-Index - 17

eISSN - 2297-475X

pISSN - 2297-4725

DOI - 10.1159/000449028

Subject(s) - dyslipidemia , medicine , metabolic syndrome , insulin resistance , diabetes mellitus , arteriosclerosis , abdominal obesity , disease , obesity , endocrine system , fatty liver , type 2 diabetes , bioinformatics , endocrinology , hormone , biology

The term metabolic syndrome (MeS) refers to a cluster of associated symptoms composed of impaired fasting glucose, abdominal obesity, hypertension, and dyslipidemia. MeS is associated with an increased risk of cardiovascular and diabetes-associated morbidity and mortality. The increased amount of visceral fat together with a chronic inflammatory state predisposes to the development of arteriosclerosis. Furthermore, insulin resistance (IR) and dyslipidemia are associated with fatty liver disease. In addition, MeS is linked to non-cardiovascular diseases such as cancer as well as psychiatric or endocrine disorders. Here, we discuss the clinical impact of MeS in cardiovascular and non-cardiovascular diseases to highlight the importance of prevention, early diagnosis, and multifactorial treatment of high-risk individuals.

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