Prevalence of Sickle Cell Trait and Reliability of Self-Reported Status among Expectant Parents in Nigeria: Implications for Targeted Newborn Screening | Zendy

Amanda R. BurnhamMarusich | Zendy; Chinenye O. Ezeanolue | Zendy; Michael Obiefune | Zendy; Wei Yang | Zendy; Alice Osuji | Zendy; Amaka G. Ogidi | Zendy; Aaron T. Hunt | Zendy; Dina Patel | Zendy; Echezona E. Ezeanolue | Zendy

Open Access

Prevalence of Sickle Cell Trait and Reliability of Self-Reported Status among Expectant Parents in Nigeria: Implications for Targeted Newborn Screening

Author(s) -

Amanda R. BurnhamMarusich,

Chinenye O. Ezeanolue,

Michael Obiefune,

Wei Yang,

Alice Osuji,

Amaka G. Ogidi,

Aaron T. Hunt,

Dina Patel,

Echezona E. Ezeanolue

Publication year - 2016

Publication title -

public health genomics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.701

H-Index - 51

eISSN - 1662-8063

pISSN - 1662-4246

DOI - 10.1159/000448914

Subject(s) - medicine , newborn screening , sickle cell trait , pediatrics , cohort , disease , demography , sociology

Sickle cell disease (SCD) is a life-threatening, autosomal recessive blood disorder prevalent in sub-Saharan Africa. We identified the prevalence of sickle cell trait (SCT) among pregnant women and their male partners in Enugu State, Nigeria, and determined the accuracy of self-reported sickle cell status and its reliability for identifying high-risk newborns for targeted screening.

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