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Ongoing Clinical Trials in Testicular Cancer: The TIGER Trial
Publication year - 2016
Publication title -
oncology research and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.553
H-Index - 48
eISSN - 2296-5262
pISSN - 2296-5270
DOI - 10.1159/000448868
Subject(s) - tiger , testicular cancer , clinical trial , cancer , medicine , oncology , computer science , computer security
In France by the PHRC (le programme hospitalier de recherche clinique), in Italy by AIFA (Agenzia Italiana del Farmaco) and in the UK by CRUK (Cancer Research UK) and the Orchid Foundation. For Germany, a grant application at the Deutsche Krebshilfe (DKH) is currently under review. The trial has been designed to prospectively assess the impact of sequential high-dose chemotherapy given at first relapse compared to conventional-dose standard chemotherapy on patients’ overall survival (OS) (primary outcome measure), as well as progressionfree survival (PFS), favorable response rate and clinically relevant parameters such as treatment related toxicity and mortality, impact of tumor marker decline rates on OS and PFS, a prospective evaDescription

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