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Increased CD69 Expression on Peripheral Eosinophils from Patients with Food Protein-Induced Enterocolitis Syndrome
Author(s) -
Taizo Wada,
Yusuke Matsuda,
Tomoko Toma,
Eiko Koizumi,
Hiroyuki Okamoto,
Akihiro Yachie
Publication year - 2016
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000448755
Subject(s) - ingestion , eosinophil , immunology , enterocolitis , eosinophil cationic protein , immune system , medicine , food allergy , cd69 , feces , allergy , biology , t cell , il 2 receptor , asthma , paleontology
Food protein-induced enterocolitis syndrome (FPIES) is an uncommon, non-IgE-mediated food allergy. We recently described a significant increase in fecal eosinophil-derived neurotoxin (EDN) after ingestion of the causative food. However, little is known about the activation status of circulating eosinophils in patients with an acute FPIES reaction.

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