Open AccessSappanone A Attenuates Allergic Airway Inflammation in Ovalbumin-Induced Asthma
Author(s) -
Xueshibojie Liu,
Duo Yu,
Tiejun Wang
Publication year - 2016
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000448331
Subject(s) - ovalbumin , immunoglobulin e , immunology , downregulation and upregulation , bronchoalveolar lavage , medicine , inflammation , asthma , allergic inflammation , pharmacology , chemistry , lung , immune system , antibody , biochemistry , gene
Sappanone A (SA) is isolated from the heartwood of Caesalpinia sappan and exerts a wide range of pharmacological activities. In the present study, we investigated the protective effects of SA on allergic asthma in a murine model of ovalbumin (OVA)-induced asthma.
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