The Effect of Glycation on Epidermal Lipid Content, Its Metabolism and Change in Barrier Function | Zendy

Mami Yokota | Zendy; Yoshihiro Tokudome | Zendy

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The Effect of Glycation on Epidermal Lipid Content, Its Metabolism and Change in Barrier Function

Author(s) -

Mami Yokota,

Yoshihiro Tokudome

Publication year - 2016

Publication title -

skin pharmacology and physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.703

H-Index - 74

eISSN - 1660-5535

pISSN - 1660-5527

DOI - 10.1159/000448121

Subject(s) - glycation , chemistry , hacat , transepidermal water loss , downregulation and upregulation , barrier function , lipid metabolism , epidermis (zoology) , carbohydrate metabolism , endocrinology , medicine , biochemistry , biology , stratum corneum , microbiology and biotechnology , receptor , in vitro , anatomy , gene , genetics

Advanced glycation end products, which are linked to both aging and hyperglycemia, cause marked functional and structural alterations in human skin. Though it is well known that the metabolism of glucose is closely associated with that of fatty acid (FA), sharing the same energy-yielding reaction pathways as glucose, its effect on the epidermis has been unclear so far.

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