Valproic Acid Promotes Human Glioma U87 Cells Apoptosis and Inhibits Glycogen Synthase Kinase-3β Through ERK/Akt Signaling | Zendy

Chi Zhang | Zendy; Songlin Liu | Zendy; Xianrui Yuan | Zendy; Zhongliang Hu | Zendy; Haoyu Li | Zendy; Ming Wu | Zendy; JianMin Yuan | Zendy; Zijin Zhao | Zendy; Jun Su | Zendy; Xiangyu Wang | Zendy; Yiwei Liao | Zendy; Qing Liu | Zendy

Open Access

Valproic Acid Promotes Human Glioma U87 Cells Apoptosis and Inhibits Glycogen Synthase Kinase-3β Through ERK/Akt Signaling

Author(s) -

Chi Zhang,

Songlin Liu,

Xianrui Yuan,

Zhongliang Hu,

Haoyu Li,

Ming Wu,

JianMin Yuan,

Zijin Zhao,

Jun Su,

Xiangyu Wang,

Yiwei Liao,

Qing Liu

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000447912

Subject(s) - ly294002 , protein kinase b , gsk 3 , pi3k/akt/mtor pathway , mapk/erk pathway , apoptosis , glioma , viability assay , signal transduction , gsk3b , biology , tunel assay , chemistry , cancer research , pharmacology , microbiology and biotechnology , biochemistry

Valproic acid (VPA), an established antiepileptic drug, was assessed for antitumor activity, including its effects on glioblastoma, but its role has not been determined.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research