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Plasma MicroRNA-126-5p is Associated with the Complexity and Severity of Coronary Artery Disease in Patients with Stable Angina Pectoris
Author(s) -
Haiyu Li,
Xin Zhao,
Yuzhou Liu,
Meng Zhe,
Dan Wang,
Fan Yang,
Qiangwei Shi
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000447794
Subject(s) - coronary artery disease , medicine , cardiology , biomarker , myocardial infarction , angina , dyslipidemia , disease , biochemistry , chemistry
Coronary artery disease (CAD) is a major problem worldwide. As an endothelium-enriched microRNA (miRNA), miR-126 has been reported to serve as a potential biomarker of acute myocardial infarction. However, the relationship between miR-126 and the severity of CAD remains unknown. This study was designed to test whether circulating miR-126 levels are associated with the severity of CAD.

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