Inhibition of Cardiomyocytes Hypertrophy by Resveratrol Is Associated with Amelioration of Endoplasmic Reticulum Stress | Zendy

Lin Yan | Zendy; Jingbin Zhu | Zendy; Xiaojie Zhang | Zendy; Jun Wang | Zendy; Wei Xiao | Zendy; Bo Li | Zendy; Jin Li | Zendy; Lian Jie | Zendy; Zhou Li | Zendy; Jicheng Liu | Zendy

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Inhibition of Cardiomyocytes Hypertrophy by Resveratrol Is Associated with Amelioration of Endoplasmic Reticulum Stress

Author(s) -

Lin Yan,

Jingbin Zhu,

Xiaojie Zhang,

Jun Wang,

Wei Xiao,

Bo Li,

Jin Li,

Lian Jie,

Zhou Li,

Jicheng Liu

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000447788

Subject(s) - endoplasmic reticulum , chop , apoptosis , muscle hypertrophy , resveratrol , western blot , atrial natriuretic peptide , unfolded protein response , medicine , endocrinology , chemistry , cell , microbiology and biotechnology , biology , pharmacology , biochemistry , gene

Resveratrol (Res), a polyphenol antioxidant found in red wine, has been shown to play a cardioprotective role. This study was undertaken to investigate whether Res can protect the heart suffering from hypertrophy injuries induced by isoproterenol (ISO), and whether the protective effect is mediated by endoplasmic reticulum (ER) stress.

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