A Subtrochanteric Femoral Stress Fracture following Bisphosphonate Treatment in an Adolescent Girl | Zendy

Alison M. Boyce | Zendy; Michael T. Collins | Zendy; Laura L. Tosi | Zendy; Rachel I. Gafni | Zendy

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A Subtrochanteric Femoral Stress Fracture following Bisphosphonate Treatment in an Adolescent Girl

Author(s) -

Alison M. Boyce,

Michael T. Collins,

Laura L. Tosi,

Rachel I. Gafni

Publication year - 2016

Publication title -

hormone research in paediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.816

H-Index - 89

eISSN - 1663-2826

pISSN - 1663-2818

DOI - 10.1159/000447425

Subject(s) - medicine , osteogenesis imperfecta , girl , bisphosphonate , osteoporosis , stress fractures , juvenile , surgery , complication , population , pediatrics , psychology , developmental psychology , environmental health , pathology , biology , genetics

Atypical subtrochanteric and diaphyseal femoral fractures (AFFs) have emerged as a potential complication of bisphosphonate treatment in adults. Despite increasing off-label use of bisphosphonates in children and adolescents for a variety of skeletal disorders, there have been no reports of AFFs in children or adolescents outside of the osteogenesis imperfecta population. We present the case of a 16-year-old girl who developed a subtrochanteric femoral stress fracture following pamidronate treatment for idiopathic juvenile osteoporosis.

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