The Lectin Complement Pathway in Patients with Necrotizing Soft Tissue Infection | Zendy

Marco Bo Hansen | Zendy; Lars S. Rasmussen | Zendy; Katrine Pilely | Zendy; Dorthe Hellemann | Zendy; Estrid Hein | Zendy; Martin Bruun Madsen | Zendy; Ole Hyldegaard | Zendy; Peter Garred | Zendy

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The Lectin Complement Pathway in Patients with Necrotizing Soft Tissue Infection

Author(s) -

Marco Bo Hansen,

Lars S. Rasmussen,

Katrine Pilely,

Dorthe Hellemann,

Estrid Hein,

Martin Bruun Madsen,

Ole Hyldegaard,

Peter Garred

Publication year - 2016

Publication title -

journal of innate immunity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.078

H-Index - 64

eISSN - 1662-8128

pISSN - 1662-811X

DOI - 10.1159/000447327

Subject(s) - hazard ratio , confidence interval , mannan binding lectin , medicine , ficolin , lectin pathway , complement system , lectin , prospective cohort study , gastroenterology , immunology , surgery , alternative complement pathway , antibody

Mannose-binding lectin (MBL) and ficolins are pattern recognition molecules (PRMs) that play an important role during infection through activation of the lectin complement pathway. We assessed whether plasma PRM levels were associated with mortality in patients with necrotizing soft tissue infection (NSTI).

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