BIOBRAD Study: The Search for Biomarkers of Bradykinin-Mediated Angio-Oedema Attacks | Zendy

A. Deroux | Zendy; Chantal DumestrePérard | Zendy; Abir KhalilMgharbel | Zendy; Maxime Maignan | Zendy; Isabelle BocconGibod | Zendy; Marie-Cécile Fevre | Zendy; Isabelle Vilgrain | Zendy; Laurence Bouillet | Zendy

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BIOBRAD Study: The Search for Biomarkers of Bradykinin-Mediated Angio-Oedema Attacks

Author(s) -

A. Deroux,

Chantal DumestrePérard,

Abir KhalilMgharbel,

Maxime Maignan,

Isabelle BocconGibod,

Marie-Cécile Fevre,

Isabelle Vilgrain,

Laurence Bouillet

Publication year - 2016

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000446959

Subject(s) - bradykinin , medicine , mast cell , abdominal pain , histamine , gastroenterology , immunology , receptor

The aetiology of angio-oedema (AE) is difficult to determine; however, it is essential in emergency situations when two major contexts may be present: mast cell-mediated AE and bradykinin-mediated AE. Different forms of AE are currently distinguished based on clinical criteria (spontaneous duration of the attack, presence of concomitant or late-appearing superficial urticaria, history of atopy, and others), but specific biomarkers could improve patient management.

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