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Serum Bicarbonate and Structural and Functional Cardiac Abnormalities in Chronic Kidney Disease - A Report from the Chronic Renal Insufficiency Cohort Study
Author(s) -
Mirela Dobre,
Jason Roy,
Kaixiang Tao,
Amanda H. Anderson,
Nisha Bansal,
Jing Chen,
Rajat Deo,
Paul E. Drawz,
Harold I. Feldman,
L. Lee Hamm,
Thomas H. Hostetter,
John W. Kusek,
Claudia M. Lora,
Akinlolu Ojo,
Kumar Shrama,
Mahboob Rahman
Publication year - 2016
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000446860
Subject(s) - medicine , kidney disease , chronic renal insufficiency , cohort , bicarbonate , cohort study , chronic renal failure , cardiology , renal function , endocrinology , intensive care medicine
Heart failure (HF) is a frequent occurrence in chronic kidney disease (CKD) patients and predicts poor survival. Serum bicarbonate is associated with increased rates of HF in CKD; however, the mechanisms leading to this association are incompletely understood. This study aims to assess whether serum bicarbonate is independently associated with structural and functional cardiac abnormalities in CKD.

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