In vivo Adsorption of Isoagglutinins with Incompatible Red Blood Cell Transfusion in Stem Cell Transplant Recipients
Author(s) -
Rainer Moog
Publication year - 2016
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000446613
Subject(s) - medicine , stem cell , in vivo , immunology , blood transfusion , red blood cell , biology , genetics , microbiology and biotechnology
In the first issue 2016 of Transfusion Medicine And Hemotherapy the transfusion support for ABO-incompatible stem cell transplantation is reviewed [1,2]. The authors focus on reduction of recipient isoagglutinins by plasmapheresis and red blood cell (RBC) depletion of the graft to avoid immune-hematologic consequences of ABO-incompatible stem cell transplantation. The old, nearly forgotten method of in vivo adsorption of recipient isoagglutinins was cited but not extensively mentioned although it is a simple, low-cost technique to circumvent immediate and delayed hemolysis after ABO-incompatible stem cell transplantation [3,4,5].
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