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In the first issue 2016 of Transfusion Medicine And Hemotherapy the transfusion support for ABO-incompatible stem cell transplantation is reviewed [1,2]. The authors focus on reduction of recipient isoagglutinins by plasmapheresis and red blood cell (RBC) depletion of the graft to avoid immune-hematologic consequences of ABO-incompatible stem cell transplantation. The old, nearly forgotten method of in vivo adsorption of recipient isoagglutinins was cited but not extensively mentioned although it is a simple, low-cost technique to circumvent immediate and delayed hemolysis after ABO-incompatible stem cell transplantation [3,4,5].

In vivo Adsorption of Isoagglutinins with Incompatible Red Blood Cell Transfusion in Stem Cell Transplant Recipients