The Medical Management of Gastro-Oesophageal Reflux Disease | Zendy

Neel Sharma | Zendy; Khek Yu Ho | Zendy

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The Medical Management of Gastro-Oesophageal Reflux Disease

Author(s) -

Neel Sharma,

Khek Yu Ho

Publication year - 2016

Publication title -

inflammatory intestinal diseases

Language(s) - English

Resource type - Journals

eISSN - 2296-9403

pISSN - 2296-9365

DOI - 10.1159/000446589

Subject(s) - medicine , gastro , reflux , gastroenterology , gastric acid , disease , proton pump inhibitor , omeprazole , weight loss , domperidone , medical therapy , smoking cessation , cisapride , ranitidine , psychological intervention , obesity , stomach , pathology , psychiatry , dopamine

Gastro-oesophageal reflux disease (GORD) is a common global phenomenon. It is associated with the backflow of gastric contents proximally, typically due to transient relaxations of the lower oesophageal sphincter. Various factors contribute to GORD, including obesity, smoking, alcohol and pregnancy. The primary concern of GORD is its association with the development over time of Barrett's oesophagus and, ultimately, oesophageal adenocarcinoma.

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