Kinship Testing Based on SNPs Using Microarray System
Author(s) -
Sohee Cho,
Hee Jin Seo,
JiHyun Lee,
Hyung Jin Yu,
Soong Deok Lee
Publication year - 2016
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000446322
Subject(s) - genetics , single nucleotide polymorphism , typing , biology , snp , population , snp genotyping , snp array , microsatellite , allele , genotype , gene , medicine , environmental health
Kinship testing using biallelic SNP markers has been demonstrated to be a promising approach as a supplement to standard STR typing, and several systems, such as pyrosequencing and microarray, have been introduced and utilized in real forensic cases. The Affymetrix microarray containing 169 autosomal SNPs developed for forensic application was applied to our practical case for kinship analysis that had remained inconclusive due to partial STR profiles of degraded DNA and possibility of inbreeding within the population.
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