Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment
Author(s) -
Veronica Tisato,
Erika Rimondi,
Gloria Brombo,
Stefano Volpato,
Amedeo Zurlo,
Giorgio Zauli,
Paola Secchiero,
Giovanni Zuliani
Publication year - 2016
Publication title -
dementia and geriatric cognitive disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.026
H-Index - 110
eISSN - 1421-9824
pISSN - 1420-8008
DOI - 10.1159/000446275
Subject(s) - dementia , vascular dementia , confounding , pathological , medicine , tumor necrosis factor alpha , oncology , cohort , univariate analysis , vascular disease , alzheimer's disease , central nervous system disease , risk factor , disease , psychology , multivariate analysis
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been involved in both physiological and pathological conditions, including vascular pathologies and pathologies of the central nervous system. Nonetheless, the knowledge about the role of systemic TRAIL in patients affected by different types of dementia and mild cognitive impairment (MCI) is still limited.
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