Novel Genetic Loci Associated with the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation
Author(s) -
Bastien Vallée Marcotte,
Hubert Cormier,
Frédéric Guénard,
Iwona Rudkowska,
Simone Lemieux,
Patrick Couture,
MarieClaude Vohl
Publication year - 2016
Publication title -
lifestyle genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 30
eISSN - 2504-3188
pISSN - 2504-3161
DOI - 10.1159/000446024
Subject(s) - single nucleotide polymorphism , triglyceride , docosahexaenoic acid , eicosapentaenoic acid , fish oil , genotype , genome wide association study , biology , fatty acid , medicine , endocrinology , polyunsaturated fatty acid , genetics , gene , cholesterol , biochemistry , fishery , fish <actinopterygii>
A recent genome-wide association study (GWAS) by our group identified 13 loci associated with the plasma triglyceride (TG) response to omega-3 (n-3) fatty acid (FA) supplementation. This study aimed to test whether single-nucleotide polymorphisms (SNPs) within the IQCJ, NXPH1, PHF17 and MYB genes are associated with the plasma TG response to an n-3 FA supplementation.
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