Open AccessNew and Evolving Immunotherapy in Inflammatory Bowel Disease
Author(s) -
Mohamad A. Raad,
Nour Chams,
Ala I. Sharara
Publication year - 2016
Publication title -
inflammatory intestinal diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9403
pISSN - 2296-9365
DOI - 10.1159/000445986
Subject(s) - immunology , immune system , inflammatory bowel disease , cytokine , ulcerative colitis , medicine , immunosuppression , disease , pathogenesis , acquired immune system , mucosal immunology , immunity
Crohn's disease and ulcerative colitis are chronic inflammatory disorders associated with a dysregulated adaptive and innate immune response to gut commensals in genetically susceptible individuals. The pathogenesis of inflammatory bowel disease is complex, and the disease is characterized by significant phenotypic and genotypic heterogeneity.
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