Transcription of Inflammatory Cytokine TNFα is Upregulated in Retinal Angiogenesis under Hyperoxia | Zendy

Yuxi Feng | Zendy; Shalini Gross | Zendy; Anupriya Chatterjee | Zendy; Yumei Wang | Zendy; Jihong Lin | Zendy; HansPeter Hammes | Zendy

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Transcription of Inflammatory Cytokine TNFα is Upregulated in Retinal Angiogenesis under Hyperoxia

Author(s) -

Yuxi Feng,

Shalini Gross,

Anupriya Chatterjee,

Yumei Wang,

Jihong Lin,

HansPeter Hammes

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000445649

Subject(s) - hyperoxia , angiogenesis , retinal , retina , vascular endothelial growth factor , neovascularization , retinopathy of prematurity , medicine , biology , ophthalmology , vegf receptors , neuroscience , lung , genetics , pregnancy , gestational age

Hypoxia induces angiogenesis while hyperoxia promotes vasoregression in the retina. We investigated herein the effect of prolonged hyperoxia on retinal angiogenesis and the underlying mechanism in an oxygen-induced retinopathy (OIR) model.

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