MicroRNA-125b Suppresses Ovarian Cancer Progression via Suppression of the Epithelial-Mesenchymal Transition Pathway by Targeting the SET Protein | Zendy

Xiaoyan Ying | Zendy; Wei Kuang | Zendy; Zhe Lin | Zendy; Yugui Cui | Zendy; Jie Ding | Zendy; Yun Chen | Zendy; Boqun Xu | Zendy

Open Access

MicroRNA-125b Suppresses Ovarian Cancer Progression via Suppression of the Epithelial-Mesenchymal Transition Pathway by Targeting the SET Protein

Author(s) -

Xiaoyan Ying,

Wei Kuang,

Zhe Lin,

Yugui Cui,

Jie Ding,

Yun Chen,

Boqun Xu

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000445642

Subject(s) - epithelial–mesenchymal transition , microrna , cancer research , downregulation and upregulation , ectopic expression , ovarian cancer , metastasis , western blot , transfection , biology , cancer , chemistry , cell culture , medicine , gene , biochemistry , genetics

MicroRNA-125b (miR-125b) is overexpressed in several types of cancer and contributes to chemotherapy resistance. However, its role in epithelial ovarian carcinoma remains unknown. The goal of this study was to identify the relationship between miR-125b and the epithelial-mesenchymal transition (EMT) in ovarian cancer.

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