Role of Myoendothelial Gap Junctions in the Regulation of Human Coronary Artery Smooth Muscle Cell Differentiation by Laminar Shear Stress | Zendy

Zongqi Zhang | Zendy; Yizhu Chen | Zendy; Tiantian Zhang | Zendy; Guo Ling-yu | Zendy; Wenlong Yang | Zendy; Junfeng Zhang | Zendy; Changqian Wang | Zendy

Open Access

Role of Myoendothelial Gap Junctions in the Regulation of Human Coronary Artery Smooth Muscle Cell Differentiation by Laminar Shear Stress

Author(s) -

Zongqi Zhang,

Yizhu Chen,

Tiantian Zhang,

Guo Ling-yu,

Wenlong Yang,

Junfeng Zhang,

Changqian Wang

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000445636

Subject(s) - gap junction , calponin , biology , microbiology and biotechnology , connexin , myocyte , intracellular , actin

Smooth muscle cells may dedifferentiate into the synthetic phenotype and promote atherosclerosis. Here, we explored the role of myoendothelial gap junctions in phenotypic switching of human coronary artery smooth muscle cells (HCASMCs) co-cultured with human coronary artery endothelial cells (HCAECs) exposed to shear stress.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research