Open AccessCardiac Contractility Modulation Attenuate Myocardial Fibrosis by Inhibiting TGF-β1/Smad3 Signaling Pathway in a Rabbit Model of Chronic Heart Failure
Author(s) -
Feifei Zhang,
Yi Dang,
Yingxiao Li,
Qingqing Hao,
Rong Li,
Xiaoyong Qi
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000445624
Subject(s) - contractility , heart failure , cardiac fibrosis , medicine , transforming growth factor , fibrosis , myocardial fibrosis , cardiology , signal transduction , endocrinology , microbiology and biotechnology , biology
Backgroun/Aims: To explore the effect of cardiac contractility modulation (CCM) on myocardial fibrosis in heart failure and to investigate the underlying mechanism.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom