Effects of 1, 25-Dihydroxyvitamin D3 on Experimental Autoimmune Myocarditis in Mice
Author(s) -
Fen Hu,
Lianhua Yan,
Shuai Lü,
Wenhan Ma,
Ya Wang,
Yuzhen Wei,
Xiaofei Yan,
Xin Zhao,
Zhijian Chen,
Zhaohui Wang,
Bo Cheng
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000445577
Subject(s) - tunel assay , myocarditis , terminal deoxynucleotidyl transferase , apoptosis , h&e stain , autophagy , blot , medicine , infiltration (hvac) , endocrinology , immunohistochemistry , chemistry , pathology , biochemistry , physics , gene , thermodynamics
Myocarditis is an important inflammatory disease of the heart which causes life-threatening conditions. 1, 25(OH)2 D3 has effects on multiple systems and diseases. The present study was aimed to investigate the effect of 1, 25(OH)2 D3 on experimental autoimmune myocarditis (EAM), and explored the underlying mechanisms involved.
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