Open AccessPerinatal Endotoxemia Induces Sustained Hepatic COX-2 Expression through an NFκB-Dependent Mechanism
Author(s) -
Sarah McKenna,
M.K. ECKMAN,
Andrew Parker,
Rachael Bok,
K. Joseph Hurt,
Clyde J. Wright
Publication year - 2016
Publication title -
journal of innate immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.078
H-Index - 64
eISSN - 1662-8128
pISSN - 1662-811X
DOI - 10.1159/000445541
Subject(s) - mechanism (biology) , nf κb , nfkb1 , chemistry , microbiology and biotechnology , medicine , immunology , biology , signal transduction , transcription factor , biochemistry , gene , physics , quantum mechanics
Exposure to perinatal infection is associated with the multiple morbidities complicating preterm birth. How a relatively immature innate immune response contributes to this is unknown.
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