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Associations of TNFα <b><i>-308G>A</i></b>, TNFα <b><i>-238G>A</i></b>,<b> </b>IL-1α <b><i>-889C>T</i></b> and IL-10 <b><i>-1082G>A </i></b>Genetic Polymorphisms with Atopic Diseases: Asthma, Rhinitis and Dermatitis
Author(s) -
Željka Babić,
Ivana Sabolić Pipinić,
Veda Marija Varnai,
Sanja Kežić,
Jelena Macan
Publication year - 2016
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000445434
Subject(s) - medicine , asthma , immunology , atopic dermatitis , allergy , cytokine
Polymorphisms of cytokine genes are an interesting focus for association studies involving atopic diseases due to their role in immune cell communications during inflammation. The aim of this study was to investigate associations of TNFα -308G>A, TNFα -238G>A, IL-1α -889C>T and IL-10 -1082G>A polymorphisms with atopic diseases with adjustment for confounding lifestyle and environmental factors.

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