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Mechanism and Therapy of Brain Edema after Intracerebral Hemorrhage
Author(s) -
Haiping Zheng,
Chunli Chen,
Jie Zhang,
Zhiping Hu
Publication year - 2016
Publication title -
cerebrovascular diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 104
eISSN - 1421-9786
pISSN - 1015-9770
DOI - 10.1159/000445170
Subject(s) - medicine , intracerebral hemorrhage , edema , hematoma , brain edema , intracranial pressure , cerebral edema , anesthesia , stroke (engine) , inflammation , surgery , subarachnoid hemorrhage , mechanical engineering , engineering
Intracerebral hemorrhage (ICH) is a subtype of stroke with a severe high mortality and disability rate and accounts for about 10-15% of all strokes. The oppression and destruction by hematoma to brain tissue cause the primary brain injury. The inflammation and coagulation response after ICH would accelerate the formation of brain edema around hematoma, resulting in a more severe and durable injury. Currently, treatments for ICH are focusing on the primary injury including reducing intracranial hypertension, blood pressure control, and rehabilitation. There is a short-of-effective medical treatment for secondary inflammation and reducing brain edema in ICH patients. So, it is very important to study on the relationship between brain edema and ICH.

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