The Role of T-Cell Subsets in Chronic Inflammation in Celiac Disease and Inflammatory Bowel Disease Patients: More Common Mechanisms or More Differences? | Zendy

Tadakazu Hisamatsu | Zendy; Ulrike Erben | Zendy; Anja A. Kühl | Zendy

Open Access

The Role of T-Cell Subsets in Chronic Inflammation in Celiac Disease and Inflammatory Bowel Disease Patients: More Common Mechanisms or More Differences?

Author(s) -

Tadakazu Hisamatsu,

Ulrike Erben,

Anja A. Kühl

Publication year - 2016

Publication title -

inflammatory intestinal diseases

Language(s) - English

Resource type - Journals

eISSN - 2296-9403

pISSN - 2296-9365

DOI - 10.1159/000445133

Subject(s) - immunology , inflammation , t cell , medicine , inflammatory bowel disease , cd8 , cytotoxic t cell , lamina propria , ulcerative colitis , proinflammatory cytokine , cytokine , disease , biology , immune system , pathology , epithelium , biochemistry , in vitro

Chronic intestinal inflammation due to noninfectious causes represents a growing health issue all over the world. Celiac disease as well as inflammatory bowel diseases (IBD) like Crohn's disease and ulcerative and microscopic colitis involve uncontrolled T-cell activation and T-cell-mediated damage as common denominators. Therefore, diagnosis and treatment decisions clearly benefit from the knowledge of the intricacies of the systemic and the local T-cell activity.

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