Increased Calcineurin A Expression Is Associated with a Lower Relapse-Free Survival Rate after Colorectal Cancer Surgery
Author(s) -
Hiroaki Niitsu,
Takao Hinoi,
Kazuhiro Sentani,
Shoichiro Mukai,
Tomohiro Adachi,
Yasufumi Saito,
Masashi Miguchi,
Masatoshi Kochi,
Haruki Sada,
Naohide Oue,
Wataru Yasui,
Hideki Ohdan
Publication year - 2016
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000445121
Subject(s) - calcineurin , immunohistochemistry , medicine , colorectal cancer , interquartile range , cancer , biomarker , hazard ratio , pathology , gastroenterology , transplantation , biology , confidence interval , biochemistry
Increased expression of calcineurin in colorectal cancer (CRC) has been reported. Although the oncogenic function has been suggested, the clinical relevance is still unclear. We herein studied calcineurin expression as a prognostic biomarker in patients receiving curative surgery for stages I-III CRC.
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