Co-Occurrence of Chronic Spontaneous Urticaria with Immunoglobulin A Deficiency and Autoimmune Diseases
Author(s) -
Barbara Frossi,
Stefano De Carli,
Fleur Bossi,
Carlo Pucillo,
Marco Carli
Publication year - 2016
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000445058
Subject(s) - immunology , medicine , autoimmunity , autoantibody , cd63 , antibody , immunoglobulin e , immune system , immunopathology , allergy , immunodeficiency , autoimmune disease , biology , microrna , biochemistry , microvesicles , gene
Immunoglobulin (Ig) A deficiency is a primary immunodeficiency in which autoimmunity is frequently observed. Thirty to fifty percent of patients with spontaneous chronic urticaria have autoantibodies that are able to cross-link FcεRI on mast cells and basophils.
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