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Omalizumab in Chronic Spontaneous Urticaria: A Brazilian Real-Life Experience
Author(s) -
Luís Felipe Ensina,
Solange Oliveira Rodrigues Valle,
Ana Paula Juliani,
Michel Galeane,
R. Vieira dos Santos,
L. Karla Arruda,
Janaína Michelle Lima Melo,
Patrícia Karla de Souza,
Faradiba Sarquis Serpa,
Djanira Andrade,
Alfeu Tavares França,
Régis A. Campos,
Inês Cristina CameloNunes,
Dirceu Solé
Publication year - 2016
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000444985
Subject(s) - omalizumab , medicine , refractory (planetary science) , chronic urticaria , adverse effect , antihistamine , gastroenterology , immunoglobulin e , immunology , antibody , physics , astrobiology
Current guidelines on chronic spontaneous urticaria (CSU) suggest a treatment based on a 3-step approach that aims at total symptom control, starting with H1-antihistamines. However, a significant number of patients present an antihistamine-resistant urticaria that must be treated with an alternative third-line therapy such as omalizumab.

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