Serum Amyloid A Type 1 Gene Polymorphism in Egyptian Children with Familial Mediterranean Fever | Zendy

Manal Wilson | Zendy; Amany A. Abou-Elalla | Zendy; Mervat T. Zakaria | Zendy; Huda Marzouk | Zendy; Hala Lotfy Fayed | Zendy; Mariam Onsy F. Hanna | Zendy

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Serum Amyloid A Type 1 Gene Polymorphism in Egyptian Children with Familial Mediterranean Fever

Author(s) -

Manal Wilson,

Amany A. Abou-Elalla,

Mervat T. Zakaria,

Huda Marzouk,

Hala Lotfy Fayed,

Mariam Onsy F. Hanna

Publication year - 2016

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000444933

Subject(s) - familial mediterranean fever , genotype , allele , medicine , biology , single nucleotide polymorphism , microbiology and biotechnology , gene , genetics , disease

Since spontaneous inflammation is an important contributor to familial Mediterranean fever (FMF), genetic variants mediating inflammation are of interest. We investigated gene variants in the acute-phase serum amyloid A type 1 (SAA1), a sensitive marker of inflammatory activity, and their association with susceptibility and severity of FMF.

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