Homocysteine in Renal Injury
Author(s) -
Yanjun Long,
Jing Nie
Publication year - 2016
Publication title -
kidney diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9381
pISSN - 2296-9357
DOI - 10.1159/000444900
Subject(s) - hyperhomocysteinemia , homocysteine , kidney disease , oxidative stress , medicine , renal function , inflammation , disease , risk factor , endocrinology , methionine , kidney , biology , biochemistry , amino acid
Homocysteine (Hcy) is an intermediate of methionine metabolism. Hyperhomocysteinemia (HHcy) can result from a deficiency in the enzymes or vitamin cofactors required for Hcy metabolism. Patients with renal disease tend to be hyperhomocysteinemic, particularly as renal function declines, although the underlying cause of HHcy in renal disease is not entirely understood.
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