Idiopathic Membranous Nephropathy: Diagnostic and Therapeutic Challenges
Author(s) -
Amr ElHusseini,
David Saxon,
Stuart Jennings,
Virgilius Cornea,
Laurence H. Beck,
B. Peter Sawaya
Publication year - 2016
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000444593
Subject(s) - medicine , nephrotic syndrome , nephropathy , membranous nephropathy , minimal change disease , hepatitis c virus , gastroenterology , glomerulonephritis , hepatitis b , renal biopsy , immunology , hepatitis c , kidney disease , hepatitis b virus , cryoglobulinemia , biopsy , kidney , focal segmental glomerulosclerosis , virus , endocrinology , diabetes mellitus
In adults, membranous nephropathy (MN) is a major cause of nephrotic syndrome. While a majority of cases of MN are idiopathic, secondary forms can be seen in the setting of autoimmune disease, neoplasia, infection, and after being exposed to certain therapeutic agents. Both human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections could cause MN. However, the effect of coexisting HIV and HCV infection on the spectrum and progression of kidney disease as well as the effect of MN treatment on HIV and HCV infection are not well known.
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