The Functional IgE-Blocking Factor Induced by Allergen-Specific Immunotherapy Correlates with IgG4 Antibodies and a Decrease of Symptoms in House Dust Mite-Allergic Children
Author(s) -
Deyu Zhao,
Xuxin Lai,
Man Tian,
Yanhe Jiang,
Yiwu Zheng,
Birgitte Gjesing,
Nanshan Zhong,
Michael D. Spangfort
Publication year - 2016
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000444391
Subject(s) - medicine , immunoglobulin e , house dust mite , asthma , immunology , blocking antibody , allergy , desensitization (medicine) , immunotherapy , allergen immunotherapy , pyroglyphidae , allergen , mite , antibody , gastroenterology , immune system , receptor , biology , botany
At present, there are no validated biomarkers reflecting or predicting the clinical efficacy of allergen-specific immunotherapy (AIT) . We aimed to investigate the correlations between clinical and immunological responses of patients undergoing house dust mite (HDM) AIT.
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