Combined Administration of Ghrelin and Corticotropin-Releasing Hormone in the Diagnosis of Cushing's Disease
Author(s) -
Dragana Miljić,
Snežana Polovina,
Mirjana Doknić,
Sandra Pekić,
Marko Stojanović,
Мilan Petakov,
Dragan Micić,
Vera Popović
Publication year - 2016
Publication title -
neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.493
H-Index - 101
eISSN - 1423-0194
pISSN - 0028-3835
DOI - 10.1159/000444281
Subject(s) - ghrelin , medicine , endocrinology , corticotropin releasing hormone , adrenocorticotropic hormone , bolus (digestion) , hormone , glucocorticoid , stimulation
Exaggerated adrenocorticotropic hormone (ACTH) and cortisol responses to ghrelin in Cushing's disease (CD) have previously been reported, similarly to responses to corticotropin-releasing hormone (CRH). We assessed the ability of ghrelin to enhance ACTH and cortisol responses when added to CRH stimulation in CD patients.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom