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Combined Administration of Ghrelin and Corticotropin-Releasing Hormone in the Diagnosis of Cushing's Disease
Author(s) -
Dragana Miljić,
Snežana Polovina,
Mirjana Doknić,
Sandra Pekić,
Marko Stojanović,
Мilan Petakov,
Dragan Micić,
Vera Popović
Publication year - 2016
Publication title -
neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.493
H-Index - 101
eISSN - 1423-0194
pISSN - 0028-3835
DOI - 10.1159/000444281
Subject(s) - ghrelin , medicine , endocrinology , corticotropin releasing hormone , adrenocorticotropic hormone , bolus (digestion) , hormone , glucocorticoid , stimulation
Exaggerated adrenocorticotropic hormone (ACTH) and cortisol responses to ghrelin in Cushing's disease (CD) have previously been reported, similarly to responses to corticotropin-releasing hormone (CRH). We assessed the ability of ghrelin to enhance ACTH and cortisol responses when added to CRH stimulation in CD patients.

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